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Metanephrines LC-MS/MS analysis kit

Metanephrines LC-MS/MS analysis kit
CE-IVD certified and suitable for any kind of LC-MS/MS instrument


The Zivak Metanephrines and Normetanephrine LC-MS/MS analysis kit can be used in combination with the Zivak-Multitasker as well as manually. Analysis run time for the manual version is just 13minutes. Due to the efficient and quite smart procedure of the Zivak-Multitasker, the automated version guarantees also to receive results in 13 minutes per test, including sample preparation-, sample injection- and analysis run time.


Quantitative LC-MS/MS analysis kit for Metanephrine and Normetanephrine in urine.

Metanephrine, Normetanephrine are primary metabolites of the epinephrine and norepinephrine catecholamines respectively. Urinary concentration of metanephrines is used to evaluate suspected pheochromocytoma. Despite the rarity of pheochromocytoma, the dangers of uncontrolled severe hypertension and the very effective surgical treatment of this condition mean that diagnosis is important. Urinary or plasma catecholamines or catecholamine-derivatives are commonly used to screen for pheochromocytomas prior to imaging. 

Zivak Urinary Metanephrines LC-MS/MS Analysis Kit was developed for accurate analysis of Metanephrine and Normetanephrine in urine samples. Main methods and procedures that we selected are based on EN ISO 13485 and 98/79/EC.

Metanephrines LC-MS/MS analysis kit 0

LC- MS/MS parameters : contact for more details

Preparation of Calibrators & Controls: contact for more details


Sample Pretreatment (Manual) : contact for more details


Materials Supplied

Order No.




1x 20 ml

Reagent 1, Contains deuterated internal standards


1x 10 ml

Reagent 2, Contains base


1 x 1 L

Mobile Phase A, Contains organic solvent


1 x 0,5 L

Mobile Phase B, Contains organic solvent


 1 x 1 L

Washing Solution, Contains organic solvent


1x 1 pc

User Guide

Materials Required But Not Supplied

Order No.




1x 8 ml

Lyophilized Urine Calibrator Level 1


1x 8 ml

Lyophilized Urine Control Level 1


1x 8 ml

Lyophilized Urine Control Level 2


1 x 1 pcs

Zivak Metanephrine Urine LC-MS/MS Analytical Column


Zivak General Catalog

Download Zivak General Catalog PDF