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VMA, HVA, 5-HIAA LC-MS/MS analysis kit

VMA, HVA, 5-HIAA LC-MS/MS analysis kit

CE-IVD certified and suitable for any kind of LC-MS/MS instrument


The Zivak VMA, HVA, 5-HIAA LC-MS/MS analysis kit can be used in combination with the Zivak-Multitasker as well as manually. Analysis run time for the manual version is just 15 minutes. Due to the efficient and quite smart procedure of the Zivak-Multitasker, the automated version guarantees also to receive results in 15 minutes per test, including sample preparation-, sample injection- and analysis run time.

Quantitative LC-MS/MS analysis kit for VMA-HVA-5-HIAA in urine.

Vanillylmandelic acid (VMA) and homovanillic acid (HVA) are final products of the catecholamine metabolism in human body. Urinary concentrations of VMA and HVA are used for screening of neuroblastoma, one of the most important tumors in children. 5-hydroxyindoleacetic acid (5-HIAA) is a metabolite of serotonin and is used for the diagnosis of carcinoid tumors.

Zivak Urinary VMA, HVA, 5-HIAA LC-MS/MS Analysis Kit was developed for accurate analysis of VMA, HVA and 5-HIAA in urine samples.

Main methods and procedures that is selected by Zivak are based on EN ISO 13485 and 98/79/EC.

VMA, HVA, 5-HIAA LC-MS/MS analysis kit 0

LC- MS/MS parameters : contact for more details 



Preparation of Calibrators and controls : contact for more details


Sample Pretreatment (Manual): contact for more details


Materials Supplied

Order No.




1x 40 ml

Reagent 1, Contains deuterated internal standards


1 x 20 ml

Reagent 2, Contains acid


2 x 1 L

Mobile Phase A, Contains organic solvent


1 x 1L

Mobile Phase B, Contains organic solvent


1 x 1 L

Washing solution, Contains organic solvent


1 x 1 pc

User Guide


Materials Required But Not Supplied

Order No.




1 x 5 ml

Lyophilised Urine Calibrator Level 1


1 x 8 ml

Lyophilised Urine Control Level 1


1 x 8 ml

Lyophilised Urine Control Level 2


1 pcs

Zivak VMA HVA 5-HIAA Urine LC-MS/MS Analytical Column


Zivak General Catalog

Download Zivak General Catalog PDF