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Carnitine / Acylcarnitines LC-MS/MS Analysis Kit (Dried Blood Spot)

Carnitine / Acylcarnitines LC-MS/MS Analysis Kit	(Dried Blood Spot)

Carnitine / Acylcarnitines LC-MS/MS analysis kit for dried blood spot.

Carnitine / Acylcarnitines screening is the most important part of the clinical diagnosis of amino acid, fatty acid or organic acid metabolism. Carnitine / Acylcarnitines screening allows to the diagnosis of over 30 metabolic diseases from a drop of blood samples taken with a screening card. This screening test occurred by measurement of Carnitine / Acylcarnitins with isotope dilution tandem mass spectrometry. LC-MS/MS is a powerful tool for gives results Carnitine / Acylcarnitines in 1.5 minutes.

Screening of following analytes can be performed by Zivak Carnitine / Acylcarnitine LC- MS/MS Analysis Kit and Zivak NeoZin Screening software. Main methods and procedures that have been selected are based on EN ISO 14971.

By the quantitative analysis of carnitine esters including such as free carnitine, C0, C2, C4, C6, C8, C10, C12, C14, C16, C16 OH, C18 , C18 OH carnitine disorders which are related with fatty acid oxidation.

By the quantitative analysis of carnitine esters including such as C3, C3DC, C4OH, C5, C5OH,C5DC carnitine, disorders which are related with organic acid metabolism.

Carnitine / Acylcarnitines LC-MS/MS Analysis Kit	(Dried Blood Spot) 0

LC-MS/MS parameters : contact for more details

 

 

 

Storage & Stability

  • It’s recommended to work in a fume hood for your safety as Reagent 2 is volatile and please avoid inhaling.
  • This analysis kit can be shipped at room temperature.
  • Controls, Reagent 2, 3 should be stored at 2-8 °C.
  • Reagent 1 should be stored at -20 °C.
  • All other components of the kit can be stored at room temperature.
  • All components are guaranteed until expiry date when stored at recommended temperatures and used as described in these instructions.

Sample Pre-treatment (Manual) : contact for more details

 

Materials Supplied

Order No.

Volume

Component

ZV-3051-02R1-15

1 x 40 ml

Reagent 1, Contains deuterated internal standards

ZV-3051-02R2-15

1 x 12 ml

Reagent 2, Contains derivatization reagent

ZV-3051-02R3-15

1 x 40 ml

Reagent 3, Contains acid

  ZV-3051-02WB-15

 1 x 0,5 L

Washing solution, Contains organic solvent

ZV-3051-02MP-15

1 x  0,6 L

Mobile Phase, Contains organic solvent

ZV-3051-KK-15

1 x 1 pc

User Manual

 
Materials Required But Not Supplied

Order No.

Volume

Component

ZV-3051-02K1-15

1 x 1 Spot

Dried Blood Spot Control Level 1

ZV-3051-02K2-15

1 x 1 Spot

Dried Blood Spot Control Level 2

ZV-3051-02S1-15

1 x 1 Spot

Dried Blood Spot Calibrator Level 1

ZV-3051-02S2-15

1 x 1 Spot

Dried Blood Spot Calibrator Level 2

ZV-3051-02C1-15

1 x 1 pcs

Zivak Carnitine / Acylcarnitines Dried Blood Spots LC-MS/MS Trap Column Holder

ZV-3051-CSPE-15

1 x 1 pcs

Carnitine / Acylcarnitines Dried Blood Spots LC-MS/MS Trap Column Cartridge

 

 

 

 

 

 

 

 

 

 

 

 

 

Zivak General Catalog

Download Zivak General Catalog PDF