Furan-2,5-dicarboxylic Acid and Furancarbonylgycine
An increase in the amount of Furan-2,5-dicarboxylic Acid and Furancarbonylglycine indicates GI mold. As a result of colonization of Aspergillus and other fungal species in the intestine, an increase in the amount of Furan-2,5-dicarboxylic acid and Furancarbonylglycine analytes is observed. Molds from dirty water and food settle in the intestine and prevent the digestive system from performing its function. In addition, studies have shown that overcooked foods increase the amount of Furan-2,5-dicarboxylic Acid and Furancarbonylglycine.
High amount of Furan-2,5-dicarboxylic Acid and Furancarbonylglycine causes intestinal dysbiosis. When the intestinal bacterial homeostasis is disrupted,dysbiosis occurs. Dysbiosis is defined by an imbalance in bacterial composition,changes in bacterial metabolic activities, or changes in bacterial distribution within the gut.
Dysbiosis has been associated with diseases such as Inflammatory Bowel Disease (IBD), obesity, Type 1 and Type 2 Diabetes, Autism, Irritable Bowel Syndrome (IBS) and certain gastrointestinal cancers.
The urine level of Furan-2,5-dicarboxylic Acid is 0-16 mmol/mol creatinine. The urine level of Furancarbonylglycine is 0-1,9 mmol/mol creatinine. Probiotic-based nutrition is recommended to reduce the amount of Furan-2,5-dicarboxylic acid and Furancarbonylglycine.
You can learn the amount of Furan-2,5-dicarboxylic Acid and Furancarbonylglycine with the Zivak Gut Microbiota Dysbiosis Marker kit, by LC-MS/MS analysis.
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