Product Categories

Neurotransmitters LC-MS/MS Analysis Kit

Neurotransmitters LC-MS/MS Analysis Kit

 

Neurotransmitters LC-MS/MS analysis kit in human urine sample

 Neurotransmitters are endogenous chemicals that transmit signals from a neuron to a target cell across a synapse. Release of neurotransmitters usually follows arrival of an action potential at the synapse, but may also follow graded electrical potentials. Neurotransmitters are synthesized from plentiful and simple precursors, such as amino acids, which are readily available from the diet and which require only a small number of biosynthetic steps to convert. Because of their importance in metabolic processes, the analysis of neurotransmitters continues to be an area of importance in chromatography. A variety of modes of HPLC can be used to retain and separate these compounds. Detection in most analyses is a significant issue since typical optical techniques have low sensitivity. Since the presence of amine groups, electrochemical methods are often used. Mass spectroscopy is now becoming the method of choice because it provides high sensitivity and identification of the analytes.

Zivak Neurotransmitters LC-MS/MS Analysis Kit was developed for accurate analysis of neurotransmitters in urine samples.

Main methods and procedures that is selected by Zivak are based on EN ISO 13485 and 98/79/EC.

Zivak Neurotransmitters LC-MS/MS Analysis Kit was developed for accurate analysis of Epinephrine, Norepinephrine, Dopamine, Serotonin, Gamma-aminobutyric acid, Glutamic Acid, Histamine, 5-Hydroxy-L-Tryptophan in urine samples. 

Neurotransmitters LC-MS/MS Analysis Kit 0
LC-MS/MS parameters : contact for more details
Storage & Stability:
  • Reagent 1,2,3,4 and calibrators, controls should be stored at between 2-8 °C.
  • Other all components of the kit should be stored at room temp.
  • Urine calibrators and control must be stored at -20 °C after reconstitution.
  • All components are guaranteed until expiry date when stored at recommended temperatures and used as described in this instructions.

 

 

Preparation of Calibrators & Controls: contact for more details

 

Materials Supplied

Order No.

Volume

Component

ZV-3033-02R1-20

1x 30ml

Reagent 1, Contains deuterated internal standard

ZV-3033-02R2-20

1x 50ml

Reagent 2, Contains base

ZV-3033-02R3-20

1x 50ml

Reagent 3, Contains base and derivatization reagent

ZV-3033-02R4-20

1x 50ml

Reagent 4, Contains organic extraction solvent

ZV-3033-02MA-20

1x1 L

Mobile Phase A, Contains organic solvent

ZV-3033-02MB-20

1x 0,5 L

Mobile Phase B, Contains organic solvent

ZV-3033-02WB-20

1x 1 L

Washing Solution

ZV-3033-KK-20

1x 1pc

User Guide

 
 
Materials Required But Not Supplied

ZV-3033-02S1-20

1x 8ml

Lyophilized Urine Calibrator Level 1

ZV-3033-02K1-20

1x 8ml

Lyophilized Urine Calibrator Level 2

ZV-3033-02K2-20

1x 8ml

Lyophilized Urine Control Level 1

ZV-3033-02C1-20

1 pcs

Zivak Neurotransmitters in Urine LC-MS/MS Analytical Column

ZS-2ML-8-1001

2x100pcs

2 ml glass autosampler vial

ZS-9004-0100-00

2x100pcs

2 ml glass autosampler vial caps pre-slit

 

Zivak General Catalog

Download Zivak General Catalog PDF